abstract：:The purpose of this study was to investigate horizontal plane localization and interaural time difference (ITD) thresholds for 14 adult cochlear implant recipients with hearing preservation in the implanted ear. Localization to broadband noise was assessed in an anechoic chamber with a 33-loudspeaker array extending f...

journal_title：Hearing research

authors： Gifford RH,Grantham DW,Sheffield SW,Davis TJ,Dwyer R,Dorman MF

更新日期：2014-06-01 00:00:00

abstract：:Several studies have reported an increased incidence of auditory dysfunction among HIV/AIDS patients. We used auditory HEI-OC1 cells in cell viability, flow cytometry and caspases 3/7-activation studies to investigate the potential ototoxicity of fourteen HIV antiretroviral agents: Abacavir, AZT, Delavirdine, Didenosi...

journal_title：Hearing research

authors： Thein P,Kalinec GM,Park C,Kalinec F

更新日期：2014-04-01 00:00:00

abstract：:The primary goal of most cochlear implant procedures is to improve a patient's ability to discriminate speech. To accomplish this, cochlear implants are programmed so as to maximize speech understanding. However, programming a cochlear implant can be an iterative, labor-intensive process that takes place over months. ...

journal_title：Hearing research

authors： Pollonini L,Olds C,Abaya H,Bortfeld H,Beauchamp MS,Oghalai JS

更新日期：2014-03-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) is a contemporary neuroimaging modality used to study connectivity patterns and microstructure of white matter tracts in the brain. The use of DTI in the study of tinnitus is a relatively unexplored methodology with no studies focusing specifically on tinnitus induced by noise exposure. ...

journal_title：Hearing research

authors： Benson RR,Gattu R,Cacace AT

更新日期：2014-03-01 00:00:00

abstract：:There is increasing evidence that humans and other nonhuman mammals are sensitive to the statistical structure of auditory input. Indeed, neural sensitivity to statistical regularities seems to be a fundamental biological property underlying auditory learning. In the case of speech, statistical regularities play a cru...

journal_title：Hearing research

authors： François C,Schön D

更新日期：2014-02-01 00:00:00

abstract：:Songbirds spend much of their time learning, producing, and listening to complex vocal sequences we call songs. Songs are learned via cultural transmission, and singing, usually by males, has a strong impact on the behavioral state of the listeners, often promoting affiliation, pair bonding, or aggression. What is it ...

journal_title：Hearing research

authors： Rothenberg D,Roeske TC,Voss HU,Naguib M,Tchernichovski O

更新日期：2014-02-01 00:00:00

abstract：:Despite advances in technology, the ability to perceive music remains limited for many cochlear implant users. This paper reviews the technological, biological, and acoustical constraints that make music an especially challenging stimulus for cochlear implant users, while highlighting recent research efforts to overco...

journal_title：Hearing research

authors： Limb CJ,Roy AT

更新日期：2014-02-01 00:00:00

abstract：:Hearing aids are a relatively non-invasive means of reducing the negative effects of hearing loss on an individual who does not require a cochlear implant. Music amplified through hearing aids has some interesting characteristics but high fidelity is not typically one of them. This poses a serious problem for the inve...

journal_title：Hearing research

authors： Chasin M,Hockley NS

更新日期：2014-02-01 00:00:00

abstract：:The ubiquity of social vocalizations among animals provides the opportunity to identify conserved mechanisms of auditory processing that subserve communication. Identifying auditory coding properties that are shared across vocal communicators will provide insight into how human auditory processing leads to speech perc...

journal_title：Hearing research

authors： Woolley SM,Portfors CV

更新日期：2013-11-01 00:00:00

abstract：:Perception of objects in the scene around us is effortless and intuitive, yet entails profound computational challenges. Progress has been made in understanding some mechanisms by which the brain encodes the boundaries and surfaces of visual objects. However, in the auditory domain, these mechanisms are poorly underst...

journal_title：Hearing research

authors： McMullan AR,Hambrook DA,Tata MS

更新日期：2013-10-01 00:00:00

abstract：:Age, drugs, and noise are major causes of acquired hearing loss. The involvement of reactive oxygen species (ROS) in hair cell death has long been discussed, but there is considerably less information available as to the mechanisms underlying ROS formation. Most cellular ROS arise in mitochondria and this review will ...

journal_title：Hearing research

authors： Böttger EC,Schacht J

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Molecular analysis using archival human inner ear specimens is challenging because of the anatomical complexity, long-term fixation, and decalcification. However, this method may provide great benefit for elucidation of otological diseases. Here, we extracted mRNA for RT-PCR from tissues dissected from archiv...

journal_title：Hearing research

authors： Kimura Y,Kubo S,Koda H,Shigemoto K,Sawabe M,Kitamura K

更新日期：2013-08-01 00:00:00

abstract：:To investigate the audio-vocal feedback responses of (F0) to hearing amplification in severe-to-profound prelingual hearing loss (SPHL) using power spectral analysis of F0 contour of sustained vowels. Sustained phonations of vowel/a/of seventeen participants with SPHL were acquired with and without hearing-aid amplifi...

journal_title：Hearing research

authors： Lee GS,Liu C,Lee SH

更新日期：2013-08-01 00:00:00

abstract：:Noise trauma, aging, and ototoxicity preferentially damage the outer hair cells of the inner ear, leading to increased hearing thresholds and poorer frequency resolution. Whereas outer hair cells make synaptic connections with less than 10% of afferent auditory nerve fibers (type-II), inner hair cells make connections...

journal_title：Hearing research

authors： Lobarinas E,Salvi R,Ding D

更新日期：2013-08-01 00:00:00

abstract：:The mastoid air cell system has traditionally been considered to have a passive role in gas exchange and pressure regulation of the middle ear possibly with some acoustic function. However, more evidence has focused on the mucosa of the mastoid, which may play a more active role in regulation of middle ear pressure. I...

journal_title：Hearing research

authors： Cros O,Borga M,Pauwels E,Dirckx JJ,Gaihede M

更新日期：2013-07-01 00:00:00

abstract：:Echolocation offers a promising approach to improve the quality of life of people with blindness although little is known about the factors influencing object localisation using a 'searching' strategy. In this paper, we describe a series of experiments using sighted and blind human listeners and a 'virtual auditory sp...

journal_title：Hearing research

authors： Rowan D,Papadopoulos T,Edwards D,Holmes H,Hollingdale A,Evans L,Allen R

更新日期：2013-06-01 00:00:00

abstract：:The superior colliculus (SC) is critical for directing accurate head and eye movements to visual and acoustic targets. In visual cortex, areas involved in orienting of the head and eyes to a visual stimulus have direct projections to the SC. In auditory cortex of the cat, four areas have been identified to be critical...

journal_title：Hearing research

authors： Chabot N,Mellott JG,Hall AJ,Tichenoff EL,Lomber SG

更新日期：2013-06-01 00:00:00

abstract：:Cochlear implant (CI) users typically have excellent speech recognition in quiet but struggle with understanding speech in noise. It is thought that broad current spread from stimulating electrodes causes adjacent electrodes to activate overlapping populations of neurons which results in interactions across adjacent c...

journal_title：Hearing research

authors： Srinivasan AG,Padilla M,Shannon RV,Landsberger DM

更新日期：2013-05-01 00:00:00

abstract：:The time of onset of hyperactivity (increased spontaneous firing rates) was investigated by single neuron recording in the inferior colliculus (IC) of guinea pigs subjected to unilateral acoustic trauma (exposure to a loud 10 kHz tone). Hyperactivity was present by 12 h post acoustic trauma whereas data obtained withi...

journal_title：Hearing research

authors： Mulders WH,Robertson D

更新日期：2013-04-01 00:00:00

abstract：:A test of within-channel detection of acoustic temporal fine structure (aTFS) cues is presented. Eight cochlear implant listeners (CI) were asked to discriminate between two Schroeder-phase (SP) complexes using a two-alternative, forced-choice task. Because differences between the acoustic stimuli are primarily constr...

journal_title：Hearing research

authors： Imennov NS,Won JH,Drennan WR,Jameyson E,Rubinstein JT

更新日期：2013-04-01 00:00:00

abstract：:Recent evidence suggests that the monkey's short-term memory in audition depends on a passively retained sensory trace as opposed to a trace reactivated from long-term memory for use in working memory. Reliance on a passive sensory trace could render memory particularly susceptible to confusion between sounds that are...

journal_title：Hearing research

authors： Scott BH,Mishkin M,Yin P

更新日期：2013-04-01 00:00:00

abstract：:Normal-hearing listeners can perceptually segregate concurrent sound sources, but listeners with significant hearing loss or who wear a cochlear implant (CI) lag behind in this ability. Perceptual grouping mechanisms are essential to segregate concurrent sound sources and affect comodulation masking release (CMR). Thu...

journal_title：Hearing research

authors： Zirn S,Hempel JM,Schuster M,Hemmert W

更新日期：2013-02-01 00:00:00

abstract：:High doses of sodium salicylate (SS) have long been known to induce temporary hearing loss and tinnitus, effects attributed to cochlear dysfunction. However, our recent publications reviewed here show that SS can induce profound, permanent, and unexpected changes in the cochlea and central nervous system. Prolonged tr...

journal_title：Hearing research

authors： Chen GD,Stolzberg D,Lobarinas E,Sun W,Ding D,Salvi R

更新日期：2013-01-01 00:00:00

abstract：:Recently, ocular vestibular evoked myogenic potentials (oVEMPs) have been described and added to the neuro-otologic test battery as a new measure for the vestibulo-ocular reflex. oVEMPs represent extraocular muscle activity in response to otolith stimulation e.g. by air-conducted sound or bone-conducted vibration. In ...

journal_title：Hearing research

authors： Kantner C,Gürkov R

更新日期：2012-12-01 00:00:00

abstract：:Georg von Békésy designed the instruments needed for his research. He also created physical models of the cochlea allowing him to manipulate the parameters (such as volume elasticity) that could be involved in controlling traveling waves. This review is about the specific devices that he used to study the motion of th...

journal_title：Hearing research

authors： Nuttall AL,Fridberger A

更新日期：2012-11-01 00:00:00

abstract：:Georg von Békésy was one of the first comparative auditory researchers. He not only studied basilar membrane (BM) movements in a range of mammals of widely different sizes, he also worked on the chicken basilar papilla and the frog middle ear. We show that, in mammals, at least, his data do not differ from those that ...

journal_title：Hearing research

authors： Manley GA,Narins PM,Fay RR

更新日期：2012-11-01 00:00:00

abstract：:This paper reviews the contributions of von Békésy to psychoacoustics, comparing his findings and interpretations to those that have emerged since his work. The areas covered include the perception of pitch for pure tones and complex tones, the effect of frequency on the apparent location of pure tones, estimation of ...

journal_title：Hearing research

authors： Moore BC

更新日期：2012-11-01 00:00:00

abstract：:Glutamate has been implicated in signal transmission between inner hair cells and afferent fibers of the organ of Corti. The inner hair cells are enriched in glutamate and the postsynaptic membranes express AMPA glutamate receptors. However, it is not known whether inner hair cells contain a mechanism for glutamate re...

journal_title：Hearing research

authors： Oguchi T,Suzuki N,Hashimoto S,Chaudhry GA,Chaudhry FA,Usami S,Ottersen OP

更新日期：2012-10-01 00:00:00

abstract：:The effect of interaural time differences (ITDs) on stream segregation for successive tone bursts was investigated. Obligatory stream segregation was inferred from the threshold for detecting a rhythmic irregularity in an otherwise isochronous sequence of interleaved "A" and "B" tones (task 1). Subjective stream segre...

journal_title：Hearing research

authors： Füllgrabe C,Moore BC

更新日期：2012-09-01 00:00:00

abstract：:The tympanic membrane is a key component of the human auditory apparatus. Good estimates of tympanic membrane mechanical properties are important to obtain realistic models of middle ear mechanics. Current literature values are almost all derived from direct mechanical tests on cut-out strips. For a biomedical specime...

journal_title：Hearing research

authors： Aernouts J,Aerts JR,Dirckx JJ

更新日期：2012-08-01 00:00:00

abstract：:The avian basilar papilla (BP) is a likely homolog of the auditory sensory epithelium of the mammalian cochlea, the organ of Corti. During mammalian development Fibroblast growth factor receptor-3 (Fgfr3) is known to regulate the differentiation of auditory mechanosensory hair cells (HCs) and supporting cells (SCs), b...

journal_title：Hearing research

authors： Jacques BE,Dabdoub A,Kelley MW

更新日期：2012-07-01 00:00:00

abstract：:Spiral ganglion cell (SGC) degeneration following hair cell loss can be prevented by administration of exogenous neurotrophic factors. Many of these neurotrophic factors, in particular the neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), have been described to be involved in the develo...

journal_title：Hearing research

authors： Ramekers D,Versnel H,Grolman W,Klis SF

更新日期：2012-06-01 00:00:00

abstract：:The auditory brainstem response (ABR) is an acoustically evoked potential commonly used to determine hearing sensitivity in laboratory animals. Both isoflurane and ketamine/xylazine anesthesia are commonly used to immobilize animals during ABR procedures. Hearing threshold determination is often the primary interest. ...

journal_title：Hearing research

authors： Ruebhausen MR,Brozoski TJ,Bauer CA

更新日期：2012-05-01 00:00:00

abstract：:The ability of auditory-nerve (AN) fibers to encode modulation frequencies, as characterized by temporal modulation transfer functions (TMTFs), generally shows a low-pass shape with a cut-off frequency that increases with fiber characteristic frequency (CF). Because AN-fiber bandwidth increases with CF, this result ha...

journal_title：Hearing research

authors： Kale S,Heinz MG

更新日期：2012-04-01 00:00:00

abstract：:One role of the inferior colliculus (IC) in bats is to create neuronal delay-tuning, which is used for the estimation of target distance in the echolocating bat's auditory system. In this study, we describe response properties of IC delay-tuned neurons of the mustached bat (Pteronotus parnellii) and compare it with th...

journal_title：Hearing research

authors： Macías S,Mora EC,Hechavarría JC,Kössl M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Recently, in vitro and in vivo models have identified that microRNAs (miRNAs), which are extensively expressed in the inner ear, play important roles in inner ear development and function. However, the function of miRNA in vertebrate tissue is not well understood. RESULTS:The current study used an in vitro ...

journal_title：Hearing research

authors： Wang XR,Zhang XM,Du J,Jiang H

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:This paper introduces a new method to calculate relative risks of elevated hearing thresholds, at various ages and frequencies, between a study population and ISO1999:2003: Annex A Screened, Annex B Unscreened and ISO1999 Section 5.3 adjustment for noise exposure using Annex A Screened data. We demonstrate th...

journal_title：Hearing research

authors： Guest M,Boggess M,Attia J,SHOAMP study team and Scientific Advisory Committee.

更新日期：2012-03-01 00:00:00

abstract：:The primary goal of this study was to characterize the variability in auditory-nerve temporal response patterns obtained with the electrically evoked compound action potential (ECAP) within and across a relatively large group of cochlear-implant recipients. ECAPs were recorded in response to each of 21 pulses in a pul...

journal_title：Hearing research

authors： Hughes ML,Castioni EE,Goehring JL,Baudhuin JL

更新日期：2012-03-01 00:00:00

abstract：:Cochlear implant performance in difficult listening situations is limited by channel interactions. It is known that partial tripolar (PTP) stimulation reduces the spread of excitation (SOE). However, the greater the degree of current focusing, the greater the absolute current required to maintain a fixed loudness. As ...

journal_title：Hearing research

authors： Landsberger DM,Padilla M,Srinivasan AG

更新日期：2012-02-01 00:00:00

abstract：:Transtympanic administration of gentamicin is a widely accepted and effective approach for treating patients with intractable vertigo. Previous studies have demonstrated the uptake, distribution and effects of gentamicin in peripheral vestibular and cochlear structures after transtympanic injection. However, little is...

journal_title：Hearing research

authors： Zhang YB,Zhang R,Zhang WF,Steyger PS,Dai CF

更新日期：2012-01-01 00:00:00